We use state-of-the art in vitro and in vivo experimental models of Parkinson’s disease, giving the possibility to validate the effectiveness and safety of new therapeutic approaches for PD.
In Vivo models
Rodents exposed to: 6OHDA, MPTP, Paraquat, AAV/alfa-sinucleina
Gavage, Intraperitoneal, Ventricle/Brain infusion, Stereotaxic brain injection
Neuronal cell line, Primary cell cultures from rodents (Dopaminergic neurons, Microglia, and Astrocytes)
Services and Evaluations
Tissues preparation and delivered to the customer, Cytotoxicity (Safety), Neuroprotective potential in vitro (efficacy), Oxidative stress levels, Neuroinflammation levels, Nigral dopaminergic neuroprotection (stereology), Alpha-synucleinopathy (histology/biochemical assays), Oxidative stress markers, Neuroinflammation, Motor behavior